Efficacy of Topical Propranolol gel in Infantile Hemangioma

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Propranolol for infantile hemangioma: An evaluation of its efficacy and safety in Iranian infants

Background: Propranolol has been recently indicated to inhibit the rapid growth and involution of infantile hemangioma. In the present study, we investigated the efficacy and safety of propranolol in Iranian infants. Methods: A total of 30 infants with indications for medical intervention, such as large hemangiomas, wounds with or without secondary infection, or active trauma-induced bleeding,...

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Propranolol therapy for infantile hemangioma.

CONTEXT There has been widespread interest surrounding the use of beta-blockers (i.e. propranolol, timolol, nadolol, acebutolol) in the treatment of infantile hemangiomas (IH). OBJECTIVE To review literature evaluating treatment of IH with propranolol. EVIDENCE ACQUISITION We conducted a literature search on PubMed and investigated for case reports, case series, and controlled trials by usi...

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Mechanisms of propranolol action in infantile hemangioma

Infantile hemangioma is a common tumor of infancy. Although most hemangiomas spontaneously regress, treatment is indicated based on complications, risk to organ development and function, and disfigurement. The serendipitous discovery of propranolol, a non-selective β-adrenergic receptor blocker, as an effective means to regress hemangiomas has made this a first-line therapy for hemangioma patie...

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[Treatment of infantile hemangioma with propranolol].

Infantile hemangiomas are proliferative vascular disorders that occur in the pediatric airway, potentially causing airway narrowing and respiratory stress. It appears in 1 out 10 children, more frequently in girls. Hemangiomas are benign tumours that usually appear on the head or neck but may also occur in deep organs. Until recently, the most common medical therapy used was high-dose systemic ...

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propranolol in infantile hemangioma: a review article

hemangioma is the most common benign cutaneous vascular tumor in infants and children. the hemangioma incidence in the neonates is 2% to 3% that increases to 10% in those younger than one year of age. before introduction of propranolol in 2008, different medications such as systemic corticosteroids and vincristine, with different side effects, were used for years. since then, over 200 studies c...

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ژورنال

عنوان ژورنال: Academic Journal of Pediatrics & Neonatology

سال: 2018

ISSN: 2474-7521

DOI: 10.19080/ajpn.2018.07.555769